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1

Strategies for improved formulation and delivery of DNA vaccines to veterinary target species

Sylvia Van Drunen Littel-van den Hurk, Shawn L. Babiuk, Lorne A. Babiuk

Journal:

Immunological Reviews

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

2

Electroporation for DNA immunization: clinical application

van Drunen Littel-van den Hurk, Sylvia, Hannaman, D

Journal:

Expert Review of Vaccines

Year:

2010

Language:

english

File:

PDF, 484 KB

english, 2010

3

Use of animal models in the development of human vaccines

Gerdts, Volker, Littel-van den Hurk, Sylvia van Drunen, Griebel, Philip J, Babiuk, Lorne A

Journal:

Future Microbiology

Year:

2007

Language:

english

File:

PDF, 485 KB

english, 2007

4

Innate and Adaptive Immune Response to Pneumonia Virus of Mice in a Resistant and a Susceptible Mouse Strain

Watkiss, Ellen, Shrivastava, Pratima, Arsic, Natasa, Gomis, Susantha, van Drunen Littel-van den Hurk, Sylvia

Journal:

Year:

2013

Language:

english

File:

PDF, 962 KB

english, 2013

5

Effects of intradermally administered plasmid deoxyribonucleic acid on ovine popliteal lymph node morphology

Richard R.E. Uwiera, Robert Rankin, Greg, P. Adams, Reno Pontarollo, Sylvia Van Drunen Littel-Van Den Hurk, Dorothy M. Middleton, Lorne, A. Babiuk, Philip J. Griebel

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2001

Language:

english

File:

PDF, 383 KB

english, 2001

6

A Distinct Role of CD4+Th17- and Th17-Stimulated CD8+CTL in the Pathogenesis of Type 1 Diabetes and Experimental Autoimmune Encephalomyelitis

Manjunatha Ankathatti Munegowda, Yulin Deng, Rajni Chibbar, Qingyong Xu, Andrew Freywald, Sean J. Mulligan, Sylvia van Drunen Littel-van den Hurk, Deming Sun, Sidong Xiong, Jim Xiang

Journal:

Journal of Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

7

A single HBsAg DNA vaccination in combination with electroporation elicits long-term antibody responses in sheep

Shawn Babiuk, Cemaine Tsang, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk, Philip J. Griebel

Journal:

Bioelectrochemistry

Year:

2007

Language:

english

File:

PDF, 338 KB

english, 2007

8

Modulation of immune responses to bovine herpesvirus-1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154

Sharmila Manoj, Philip J. Griebel, Lorne A. Babiuk, Sylvia Van Drunen Littel-Van Den Hurk

Journal:

Year:

2004

Language:

english

File:

PDF, 344 KB

english, 2004

9

TLR9−/− and TLR9+/+ mice display similar immune responses to a DNA vaccine

Shawn Babiuk, Neeloffer Mookherjee, Reno Pontarollo, Phillip Griebel, Sylvia Van Drunen Littel-Van Den Hurk, Rolf Hecker, Lorne Babiuk

Journal:

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

10

10.1038/78699

Griebel, Philip J., Gerdts, Volker, Babiuk, Lorne A., van Drunen Littel-van den Hurk, Sylvia

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

11

Bovine herpesvirus-1 vaccines

van Drunen Littel-van den Hurk, Sylvia, Tikoo, Suresh K, Liang, Xiaoping, Babiuk, Lorne A

Journal:

Immunology & Cell Biology

Year:

1993

Language:

english

File:

PDF, 5.97 MB

english, 1993

12

Identification and Transcriptional Analysis of a 3′-Coterminal Gene Cluster Containing UL1, UL2, UL3, and UL3.5 Open Reading Frames of Bovine Herpesvirus-1

Sunil K. Khattar, Sylvia Van Drunen Littel-Van Den Hurk, Lorne A. Babiuk, Suresh K. Tikoo

Journal:

Year:

1995

File:

PDF, 705 KB

1995

13

Identification and Characterization of a Bovine Herpesvirus-1 (BHV-1) Glycoprotein gL Which Is Required for Proper Antigenicity, Processing, and Transport of BHV-1 Glycoprotein gH

SUNIL K. KHATTAR, SYLVIA VAN DRUNEN LITTEL-VAN DEN HURK, SAM K. ATTAH-POKU, LORNE.A. BABIUK, SURESH K. TIKOO

Journal:

Year:

1996

Language:

english

File:

PDF, 217 KB

english, 1996

14

The Cytoplasmic Domain of Bovine Herpesvirus 1 Glycoprotein B Is Important for Maintaining Conformation and the High-Affinity Binding Site of gB

Yuanhao Li, Sylvia Van Drunen Littel-Van Den Hurk, Xiaoping Liang, Lorne A. Babiuk

Journal:

Year:

1996

Language:

english

File:

PDF, 374 KB

english, 1996

15

Functional Analysis of the Transmembrane Anchor Region of Bovine Herpesvirus 1 Glycoprotein gB

YUANHAO LI, SYLVIA VAN DRUNEN LITTEL-VAN DEN HURK, XIAOPING LIANG, LORNE A BABIUK

Journal:

Year:

1997

Language:

english

File:

PDF, 861 KB

english, 1997

16

Bovine Herpesvirus 1-Induced Apoptotic Cell Death: Role of Glycoprotein D

Emmanuel Hanon, Günther Keil, Sylvia van Drunen Littel-van den Hurk, Philip Griebel, Alain Vanderplasschen, Frans A.M. Rijsewijk, Lorne Babiuk, Paul-Pierre Pastoret

Journal:

Year:

1999

Language:

english

File:

PDF, 104 KB

english, 1999

17

Glycoprotein D Homologs in Herpes Simplex Virus Type 1, Pseudorabies Virus, and Bovine Herpes Virus Type 1 Bind Directly to Human HveC (Nectin-1) with Different Affinities

Sarah A. Connolly, J.Charles Whitbeck, Ann H. Rux, Claude Krummenacher, Sylvia van Drunen Littel-van den Hurk, Gary H. Cohen, Roselyn J. Eisenberg

Journal:

Year:

2001

Language:

english

File:

PDF, 248 KB

english, 2001

18

Mapping of 10 epitopes on bovine herpesvirus type 1 glycoproteins gl and glll

David R. Fitzpatrick, Mark J. Redmondz, Sam K. Attah-Poku, Sylvia Van Drunen Littel-Van Den Hurk, Lorne A. Babiuk, Tim J. Zamb

Journal:

Year:

1990

Language:

english

File:

PDF, 3.59 MB

english, 1990

19

Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotides

George Mutwiri, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk

Journal:

Advanced Drug Delivery Reviews

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

20

Rationale and perspectives on the success of vaccination against bovine herpesvirus-1

Sylvia van Drunen Littel-van den Hurk

Journal:

Veterinary Microbiology

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

21

Characterization of nuclear localization and export signals of the major tegument protein VP8 of bovine herpesvirus-1

Chunfu Zheng, Robert Brownlie, Lorne A Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2004

Language:

english

File:

PDF, 675 KB

english, 2004

22

Formulation with CpG oligodeoxynucleotides increases cellular immunity and protection induced by vaccination of calves with formalin-inactivated bovine respiratory syncytial virus

John W. Mapletoft, Mustapha Oumouna, Hugh G. Townsend, Susantha Gomis, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2006

Language:

english

File:

PDF, 265 KB

english, 2006

23

Intracellular trafficking of VP22 in bovine herpesvirus-1 infected cells

Vladislav A. Lobanov, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2010

Language:

english

File:

PDF, 1.85 MB

english, 2010

24

Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses

Sharmila Manoj, Lorne A Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2003

Language:

english

File:

PDF, 389 KB

english, 2003

25

Synthesis and processing of bovine herpesvirus-1 glycoprotein H

Eric Baranowski, Jean Dubuisson, Sylvia van Drunen Littel-van den Hurk, A. Lorne Babiuk, Alain Michel, Paul-Pierre Pastoret, Etienne Thiry

Journal:

Year:

1995

Language:

english

File:

PDF, 769 KB

english, 1995

26

Recent advances in the use of DNA vaccines for the treatment of diseases of farmed animals

Sylvia van Drunen Littel-van den Hurk, Volker Gerdts, Bianca I Loehr, Reno Pontarollo, Robert Rankin, Richard Uwiera, Lorne A Babiuk

Journal:

Advanced Drug Delivery Reviews

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

27

Evaluation of baculovirus-expressed bovine herpesvirus-1 (BHV-1) glycoproteins for detection and analysis of BHV-1-specific antibody responses

Omar Y Abdelmagid, Mahmoud M Mansour, Harish C Minocha, Sylvia van Drunen Littel-van den Hurk

Journal:

Veterinary Microbiology

Year:

1998

Language:

english

File:

PDF, 161 KB

english, 1998

28

Dendritic cells matured by a prostaglandin E2-containing cocktail can produce high levels of IL-12p70 and are more mature and Th1-biased than dendritic cells treated with TNF-α or LPS

Abdolamir Landi, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2011

Language:

english

File:

PDF, 2.26 MB

english, 2011

29

Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8

Jianzhong Zhu, Sylvia van Drunen Littel-van den Hurk, Robert Brownlie, Lorne A. Babiuk, Andrew Potter, George K. Mutwiri

Journal:

Molecular Immunology

Year:

2009

Language:

english

File:

PDF, 1.95 MB

english, 2009

30

Synthetic peptide vaccination in cattle: induction of strong cellular immune responses against peptides derived from the Mycobacterium bovis antigen Rv3019c

H. Martin Vordermeier, Reno Pontarollo, Brenda Karvonen, Paul Cockle, Rolf Hecker, Mahavir Singh, Lorne A. Babiuk, R. Glyn Hewinson, Sylvia van Drunen Littel-van Den Hurk

Journal:

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

31

Immunization with plasmid DNA encoding a truncated, secreted form of the bovine viral diarrhea virus E2 protein elicits strong humoral and cellular immune responses

Rong Liang, Jan V. van den Hurk, Chunfu Zheng, Hong Yu, Reno A. Pontarollo, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2005

Language:

english

File:

PDF, 429 KB

english, 2005

32

Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D

Chunfu Zheng, Christiane Juhls, Detlef Oswald, Florian Sack, Ines Westfehling, Burghardt Wittig, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2006

Language:

english

File:

PDF, 306 KB

english, 2006

33

Immunity and protection by adoptive transfer of dendritic cells transfected with hepatitis C NS3/4A mRNA

Hong Yu, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2007

Language:

english

File:

PDF, 964 KB

english, 2007

34

A single DNA immunization in combination with electroporation prolongs the primary immune response and maintains immune memory for six months

Cemaine Tsang, Shawn Babiuk, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk, Philip Griebel

Journal:

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

35

Compatibility of plasmids encoding bovine viral diarrhea virus type 1 and type 2 E2 in a single DNA vaccine formulation

Rong Liang, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2007

Language:

english

File:

PDF, 933 KB

english, 2007

36

Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A

Erin Scruten, Jennifer Kovacs-Nolan, Philip J. Griebel, Laura Latimer, Jason Kindrachuk, Andy Potter, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk, Scott Napper

Journal:

Year:

2010

Language:

english

File:

PDF, 1.46 MB

english, 2010

37

Electroporation enhances immune responses and protection induced by a bovine viral diarrhea virus DNA vaccine in newborn calves with maternal antibodies

Sylvia van Drunen Littel-van den Hurk, Zoe Lawman, Don Wilson, Alain Luxembourg, Barry Ellefsen, Jan V. van den Hurk, Drew Hannaman

Journal:

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

38

A novel triple adjuvant formulation promotes strong, Th1-biased immune responses and significant antigen retention at the site of injection

Heather L. Wilson, Jennifer Kovacs-Nolan, Laura Latimer, Rachelle Buchanan, Susantha Gomis, Lorne Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

39

The synthetic peptides bovine enteric β-defensin (EBD), bovine neutrophil β-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells

Sarah Mackenzie-Dyck, Sam Attah-Poku, Veronique Juillard, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Veterinary Immunology and Immunopathology

Year:

2011

Language:

english

File:

PDF, 2.44 MB

english, 2011

40

Phylogeny and antigenic relationships of three cervid herpesviruses

Dirk Deregt, Scott A. Gilbert, Iris Campbell, Kimberley M. Burton, Hugh W. Reid, Sylvia van Drunen Littel-van den Hurk, Carolyn Penniket, Mohit K. Baxi

Journal:

Year:

2005

Language:

english

File:

PDF, 614 KB

english, 2005

41

Bovine herpesvirus-1 VP8 interacts with DNA damage binding protein-1 (DDB1) and is monoubiquitinated during infection

Natalya L. Vasilenko, Marlene Snider, Shaunivan L. Labiuk, Vladislav A. Lobanov, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk

Journal:

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

42

Fusion of C3d molecule with bovine rotavirus VP7 or bovine herpesvirus type 1 glycoprotein D inhibits immune responses following DNA immunization

Sanipa Suradhat, Ralph P. Braun, P.Jeffrey Lewis, Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk, Philip J. Griebel, Maria E. Baca-Estrada

Journal:

Veterinary Immunology and Immunopathology

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

43

Polynucleotide vaccines in animals: enhancing and modulating responses

P.Jeffrey Lewis, Graham J.M. Cox, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk

Journal:

Year:

1997

Language:

english

File:

PDF, 539 KB

english, 1997

44

Pathogenesis of respiratory syncytial virus

Sylvia van Drunen Littel-van den Hurk, Ellen R Watkiss

Journal:

Current Opinion in Virology

Year:

2012

Language:

english

File:

PDF, 295 KB

english, 2012

45

Carrier molecules for use in veterinary vaccines

Gerdts, Volker, Mutwiri, George, Richards, James, Hurk, Sylvia van Drunen Littel-van den, Potter, Andrew A.

Journal:

Year:

2013

Language:

english

File:

PDF, 275 KB

english, 2013

46

Cell-mediated immune responses induced by BHV-1: rational vaccine design

van Drunen Littel-van den Hurk, Sylvia

Journal:

Expert Review of Vaccines

Year:

2007

Language:

english

File:

PDF, 444 KB

english, 2007

47

Interactions of monoclonal antibodies and bovine herpesvirus type 1 (BHV-1) glycoproteins: Characterization of their biochemical and immunological properties

Sylvia Van Drunen Littel-Van Den Hurk, Jan V. Van Den Hurk, James E. Gilchrist, Vikram Misra, Lorne A. Babiuki

Journal:

Year:

1984

Language:

english

File:

PDF, 2.61 MB

english, 1984

48

Effect of tunicamycin and monensin on biosynthesis, transport, and maturation of bovine herpesvirus type-1 glycoproteins

Sylvia Van Drunen Littel-Van Den Hurk, L.A. Babiuki

Journal:

Year:

1985

Language:

english

File:

PDF, 5.44 MB

english, 1985

49

Topographical analysis of bovine herpesvirus type-1 glycoproteins: Use of monoclonal antibodies to identify and characterize functional epitopes

Sylvia Van Drunen Littel-van den Hurk, Jan V. van den Hurk, Lorne A. Babiuk

Journal:

Year:

1985

Language:

english

File:

PDF, 1.03 MB

english, 1985

50

Antigenic and immunogenic characteristics of bovine herpesvirus type-1 glycoproteins GVP 39 and GVP 6/11a/16, purified by immunoadsorbent chromatography

Sylvia Van Drunen, Littel-Van Den Hurk, Lorne A. Babiuk

Journal:

Year:

1985

Language:

english

File:

PDF, 2.00 MB

english, 1985

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